Ocular irritation: present cell culture models and perspectives
By Guillot, R.
| Record number: | 1664900 |
|---|---|
| Category: | animal use alternatives - eyes - cultured cells |
Various cell culture models have been proposed as partial or total replacements for in vitro ocular irritation tests. The cytotoxic potential of substances can be evaluated according to various parameters for measuring cellular viability and metabolic capacity. Cell cultures have their limitations, but they also have advantages which justify the inclusion of some such models in a battery of in vitro tests that could replace the Draize test.
Issued: July 1992
Journal Title: Alternatives to laboratory animals
ISSN: 0261-1929
Volume issue: 20 v. 3 no.
Pages: 471 - 475
Notes:
Paper presented at the third meeting of the Societe de Pharmacologie Cellulaire on "Alternatives to ocular irritation," October 18, 1991, Paris.
AGRICOLA identifier: IND20354844
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