FRAME and the Validation Process
By Balls, Michael - Clothier, Richard
| Record number: | 2234613 |
|---|---|
| Category: | model validation - acute toxicity - phototoxicity - cytotoxicity - animal use alternatives |
FRAME’s historical involvement in the development of the principles of validation, whereby the reliability and relevance of a procedure are established for a specific purpose, and in the practical application of the process, is summarised, and examples of participation in various validation studies on in vitro tests are reviewed. Emphasis is placed on the need for a parallel invalidation process, and on the role of ATLA as a forum for objective reporting and discussion on all aspects of the validation process.
Issued: Dec. 2009
Journal Title: Alternatives to laboratory animals
ISSN: 0261-1929
Volume issue: 37 v. 6 no.
Pages: 631–640 - 631–640
AGRICOLA identifier: IND44337481
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