In vitro cytotoxicity of 26 coded chemicals to HEp-2 cells: a validation study
By Mazziotti, I. - Stammati, A.L. - Zucco, F.
| Record number: | 2928242 |
|---|---|
| Category: | animal use alternatives - cytotoxicity - validity |
Twenty-six chemicals supplied coded by FRAME, were tested on HEp-2 cells. Three endpoints were used to measure the cytotoxicity of these compounds: total protein content, LDH release and total acid phosphatase content. The sensitivity of these parameters is discussed. The results are compared with those obtained by other groups participating in the validation scheme organised by FRAME.
Issued: June 1990
Journal Title: Alternatives to laboratory animals
ISSN: 0261-1929
Volume issue: 17 v. 4 no.
Pages: 401 - 406
AGRICOLA identifier: IND20369633
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