An alternative test using algal cultures for testing chemicals for toxicity
By Nielsen, S.A. - Hougaard, T.
| Record number: | 1667866 |
|---|---|
| Category: | animal use alternatives - algae and seaweeds - Selenastrum capricornutum |
An alternative test is presented, in which algal cultures are used for testing toxic substances. This test system is based on variations in the size distribution of cells in test cultures as a measurement of growth. Thus, inhibition of mitotic activity is used as a measurement for toxic effects. The test can be performed on a short time-scale and is very sensitive to even weak toxic doses.
Issued: Apr 1993
Journal Title: Alternatives to laboratory animals
ISSN: 0261-1929
Volume issue: 21 v. 2 no.
Pages: 196 - 201
Notes:
Paper presented at the tenth annual Scandinavian Society of Cell Toxicology conference on in vitro toxicology, Sept 10-13, 1992, Visby, Gotland, Sweden.
AGRICOLA identifier: IND20359612
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